Which statement about wound healing is true?

Which statement about wound healing is true?

• A. Inflammation is the only phase
• B. Proliferation involves collagen deposition
• C. Remodeling occurs before inflammation
• D. Coagulation is part of remodeling

Answer: (B)

Wound healing progresses through several overlapping stages: hemostasis, inflammation, proliferation, and remodeling. During the proliferation phase, fibroblasts lay down collagen and other extracellular matrix components to form granulation tissue and provide a scaffold for new tissue. This collagen deposition is a hallmark of the proliferative process, helping to close the wound and support revascularization and epithelialization. The other statements don’t fit the sequence or roles of the phases: inflammation is not the only phase, as proliferation and remodeling follow and overlap with it; remodeling occurs after proliferation, not before; and coagulation is part of hemostasis at the wound’s outset, not a component of remodeling.

Wound healing progresses through several overlapping stages: hemostasis, inflammation, proliferation, and remodeling. During the proliferation phase, fibroblasts lay down collagen and other extracellular matrix components to form granulation tissue and provide a scaffold for new tissue. This collagen deposition is a hallmark of the proliferative process, helping to close the wound and support revascularization and epithelialization.

The other statements don’t fit the sequence or roles of the phases: inflammation is not the only phase, as proliferation and remodeling follow and overlap with it; remodeling occurs after proliferation, not before; and coagulation is part of hemostasis at the wound’s outset, not a component of remodeling.